Development of Novel and Emerging Technologies to Support Zebrafish Models for Biomedical Research (SBIR)(R41/R42)

Incentive Type: Grant Program
Health And Safety, Research, Technology
Eligible Sector:
Financial Incentive
Time Period:
FY 2015
Governing Body: National Institutes of Health
What’s it worth?: Not mentioned

The Development of Novel and Emerging Technologies to Support Zebrafish Models for Biomedical Research purpose is to fund research that uses zebrafish models of biomedical value to develop technology to support the diverse aspects of the creation, detection, identification and characterization of zebrafish models of human disease and prevention of genetic stocks. Ideal development and enhancement efforts include but are not excluded to:

  • High throughput system that increase the speed of phenotypic and toxicological analysis.
  • Software used for the automation and standardization of embryo position
  • Genetic methods to speed up production of knockout fish with reduced off-target effects.
  • Methods and devices used for recording and data analysis.
  • Preservation of genetic stocks.
  • Production of biological reagents.
  • Detection of biological markers.
  • Non-fluorescence methods to measure gene expression
  • Methods to monitor food intake.
  • Development of humanized models.
  • Creation of fluorescent fish lines
  • Identification and tagging software.
  • Athogen detection.
  • Sex determination of embryos, larvae, juveniles and adults.

Typical award amounts of not more than $225,000 for Phase I projects and up to $1,500,000 for Phase II projects with project duration of up to two years. All applicants must meet the following criteria:

  • Applicant must be an organized for-profit organization located within the U.S. and operating in the U.S.
  • Is in the legal form of an:

– Individual proprietorship
– Partnership
– Limited liability company
– Corporation
– Joint venture
– Association
– Trust or cooperative

  • Must be less than 50% foreign participation
  • Be more than 50% directly owned and controlled by one or more individuals who are U.S. citizens
  • SBIR must be more than 50% owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these.
  • Be a joint venture
  • Does not have more than 500 employees

Applicants must registered with:

  • Dun and Bradstreet Universal Number System (DUNS)
  • System for Award Management (SAM)
  • SBA Company Registry
  • eRA Commons

This program does not have any cost sharing requirements. Applications must be complete and received before the deadline; however, it is strongly encouraged that eligible applicants contact the NIH program officials before submitting any applications in excess of the guidelines.