Maryland Patent of the Month – August 2024
RNAimmune, Inc., an mRNA biotech company, has developed a new medicine to treat COVID-19. This breakthrough leverages the power of mRNA to instruct cells to produce viral proteins, specifically the spike (S) protein, which triggers a robust immune response without the need for a live virus.
What sets RNAimmune’s approach apart is the use of polymeric nanoparticles to deliver the mRNA effectively into cells. These nanoparticles are crafted from a unique blend of carriers, including histidine-lysine co-polymers (HKP) and lipids, which not only protect the mRNA but also enhance its stability and delivery efficiency. This sophisticated delivery system ensures that the mRNA reaches its target, leading to the production of viral proteins that prime the immune system to recognize and fight the real virus.
The composition also incorporates cutting-edge chemical modifications, such as N1-methyl-pseudouridine, which boosts the stability and translational efficiency of the mRNA. These modifications are crucial in enhancing the vaccine’s effectiveness and safety, ensuring a strong and sustained immune response with minimal side effects.
RNAimmune’s innovation doesn’t stop at just preventing infection. Their mRNA composition can also be administered through various methods, including subcutaneous or intramuscular injections, and even via a nebulizer for direct delivery to the respiratory tract. This versatility makes it a powerful tool not only for prevention but also for therapeutic intervention in those already infected.
Are you developing new technology for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.
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