Massachusetts Patent of the Month – December 2022

Rapid Micro Biosystems, Inc. develops groundbreaking technology and products to support biomanufacturing companies. One such avenue of development is focused on accelerating the detection of microbial contamination in the manufacture of pharmaceuticals, biologics, medical devices, personal care products and more. The faster we can get results, the more readily we can manage and improve patient outcomes. For that reason, the company has worked towards developing rapid detection capabilities for replicating cells.

Their recently patented system enables the rapid replication of living cells by detecting microscopic colonies derived from cell division. The living target cells in the sample are observed and allowed to form microcolonies within a detection area. The target cells are randomly dispersed and immobilized within the detection area and the microcolonies are observed. The true genius of this method lies in the ability to detect microcolonies containing only a small fraction of the cells that are required by traditional methods. Since cell replication takes time, detecting small colonies is inherently faster.

The company achieves this small colony detection with a combination of signal generation and signal detection methods. This, combined with a large area imaging, achieves ultra-sensitivity.

The technology developed by Rapid Micro Biosystems replaces slow, error-prone manual processes and improves data integrity. It also enables manufacturers to accelerate timelines, maximize capacity, and reduce operational risk and downtime. This results in better, more cost-effective pharmaceuticals, biologics, biotech products, medical devices, and personal care products.

Are you developing new technology for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

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