Mesa, Arizona Patent of the Year – 2024/2025
Mirror Biologics Inc. has been awarded the 2024/2025 Patent of the Year for its groundbreaking immunotherapy innovation. Their invention, detailed in U.S. Patent No. 11883490, titled ‘Induction of IL-12 using immunotherapy’, employs activated allogeneic immune cells to safely induce interleukin-12 (IL-12) production, enhancing the body’s defense against cancer and infectious diseases.
This novel approach stimulates a Th1-type immune response, crucial for combating tumors and pathogens. By administering these activated cells, the therapy elevates IL-12 levels in patients’ plasma without the toxicity typically associated with direct IL-12 treatments. This advancement offers a safer, more effective method to boost the immune system’s natural defenses.
The technology is part of Mirror Biologics’ Mirror Effect® platform, which leverages the body’s own immune mechanisms to target diseases. Unlike traditional therapies requiring genetic modification or immunosuppression, this method uses non-genetically altered, off-the-shelf immune cells, simplifying treatment and reducing risks.
By harnessing the body’s innate ability to fight disease, Mirror Biologics’ innovation represents a significant step forward in immunotherapy. It holds promise for treating a range of conditions, including various cancers and infectious diseases, by enhancing the immune system’s capacity to respond effectively.