Carbondale, Illinois Patent of the Year – 2024/2025
Southern Illinois University has been awarded the 2024/2025 Patent of the Year for its innovative approach to hearing restoration. Their invention, detailed in U.S. Patent No. 12162935, titled ‘Regimens, compositions and methods with capsaicin and TNF-alpha inhibitor’, introduces a novel treatment combining capsaicin and TNF-alpha inhibitors to repair auditory damage and restore hearing.
This new therapy targets the repair of damaged auditory hair cells, synapses, and neurons. By using capsaicin – a compound known for its presence in chili peppers – and TNF-alpha inhibitors like etanercept, the regimen aims to reduce inflammation and promote healing within the inner ear. This combination offers a potential breakthrough for individuals experiencing hearing loss due to factors such as noise exposure, chemotherapy, or aging.
The treatment can be administered through various methods, including oral and injectable forms, providing flexibility for patient needs. The approach not only seeks to prevent further auditory damage but also to restore existing hearing loss, marking a significant advancement in audiological care.
Southern Illinois University’s development represents a promising step forward in addressing hearing impairment. By focusing on both prevention and restoration, this patent could lead to more effective treatments and improved quality of life for those affected by hearing loss.
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