Rhode Island Patent of the Month – June 2025

In a promising development for cancer research, VeroScience LLC has secured U.S. Patent No. 12318451 for a novel approach to tumor regression. The invention details a method that uses hormonal timing and metabolic control to trigger natural immune responses and shrink solid tumors.

Reprogramming the tumor environment

The patented method uses somatostatin analogs to influence the body’s circadian rhythm and insulin regulation. By administering these compounds in a timed-release schedule, the process alters glucose metabolism in a way that destabilizes tumor growth conditions. The technique does not target cancer cells directly but changes the environment they depend on.

New ground in cancer therapy

This approach stands apart from traditional therapies like chemotherapy or radiation. Rather than killing cells outright, it aims to make the tumor’s survival mechanisms unsustainable. The result is a potentially less toxic treatment that could benefit patients who are not candidates for aggressive interventions.

Broader therapeutic potential

VeroScience LLC indicates the method may apply to a wide range of solid tumors, including pancreatic, liver, and breast cancers. It also opens possibilities for combination therapies where metabolic reprogramming supports other cancer treatments.

This innovation underscores a growing trend in cancer R&D: targeting systemic processes to drive localized effects. By shifting focus to the body’s internal rhythms, it offers a new frontier in oncology strategy.

 

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