South Carolina Patent of the Month – May 2021

Scaffold-based tissue engineering approaches have largely focused on the use of 3D microenvironments to grow cardiac tissue. These scaffolds are lacking some important components including the chemical and biological properties of native extracellular environments of the myocardium. The alternative – which is scaffold-free 3D cardiac spheroids are prepared by seeding cardiomyocytes into agarose microwells. This method does produce improved cardiac function but formation is not as controlled and can ultimately produce unsynchronized contractions. Musc Foundation for Research Development has designed a new method to develop cardiac tissues containing semiconductor nanomaterials.

Their method involves seeding a substrate in an agarose gel with a cell suspension as well as semiconductor nanomaterial, creating a cell culture. The cell culture will then be electrically stimulated periodically using nanoscale semiconductors.. The cardiomyocytes can be grown in a controlled formation using scaffolding. This method brings the best of both traditional methods, and introduces electrical stimulation to produce the most functional synthesized tissue.

Are you developing new technology for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

Who We Are:

Swanson Reed is one of the U.S.’ largest Specialist R&D tax advisory firms. We manage all facets of the R&D tax credit program, from claim preparation and audit compliance to claim disputes.

Swanson Reed regularly hosts free webinars and provides free IRS CE and CPE credits for CPAs. For more information please visit us at or contact your usual Swanson Reed representative.

Recent Posts