Georgia Patent of the Month – July 2021

Know Biological, Inc. is a life science company that combines software with the medical industry to advance detection and treatment opportunities. Epilepsy is a neurological disorder of the central nervous system. Two thirds of epilepsy patients can effectively control their seizures through medication – but the remaining third experience uncontrolled and unpredictable seizure episodes. Often, the unpredictability is a large consequence itself – taking away independence and causing anxiety. Know Biological has developed a seizure detection device which gathers data off a patient’s skin and providing a warning to the patient.

Their device collects volatile organic compounds from the patent’s skin. A heating element within the device emits a thermal pulse, desorbing the compounds from the collector material. These compounds are then run through a gas chromatography column, separating them into their separate chemicals and analyzed by a processor. Certain organic compounds are known to indicate a seizure, These compounds rise in the pre-seizure stage, and can appear in different concentrations depending on the individual’s blood chemistry. This pre-seizure phase can appear anywhere from 5 to 40 minutes before a seizure occurs, giving a warning to the patient. This gives the patient a chance to sit down or get off the road, getting themselves into a safe position or calling for help beforehand. Removing that sense of unpredictability gives patients with epilepsy more control over their own life again.

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