Ohio Patent of the Month – January 2023
COVID-19 brought the virus strain, known as Coronavirus, to the public spotlight. This highly infectious group of viruses are characterized by a unique appearance, with a fringe reminiscent of a crown or halo, which led to their name being derived from the Latin word “corona.” As with all viruses, they have a single strand of RNA which makes up their genome.
Analiza Inc, an inventor in the field of viral detection and identification, has recently patented an RNA separation technique which makes it possible to determine the presence of viruses such as coronaviruses. These methods involve partitioning a biological fluid containing the virus and free nucleic acid in an aqueous multi-phase partitioning system. Free RNA and nucleic acids are preferentially partitioned into one phase while intact viruses are partitioned in the other phase. The virus can then be determined within the partitioning system, the degree of infectiousness can be determined, and the free nucleic acid can be sequenced to provide further information. One of the key advantages of the methods developed by Analiza is that at least 95% of the free nucleic acid partitions are in the first phase of the partitioning system, allowing for efficient and accurate analysis.
Analiza’s systems and methods offer a reliable and efficient way of determining the presence of coronaviruses and could play a vital role in the ongoing fight against these highly infectious diseases. Analiza is a leading contract research organization dedicated to discovering, developing, and commercializing new technologies for the life sciences. Analiza provides integrated solutions to key applications in the pharmaceutical, biotechnology and diagnostics industries.
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