Alabama Patent of the Month – January 2024
CerFlux, Inc., innovators in cancer research, have been granted a patent for their proprietary biomimetic array device, poised to redefine the landscape of biological sample analysis. This groundbreaking invention presents a meticulously crafted cassette, featuring a microchamber array and microchannels that pave the way for innovative applications in fluid transport and equal exposure of biological samples.
At the heart of this device lies a series of microchambers in fluid communication with microchannels, forming a network primed for intricate biological sample interactions. The top interface of each microchamber, open to its external environment, serves as a receptacle for biological samples. This setup allows the sample to draw fluid from the microchambers, pulling the same volume from each chamber.
The biomimetic array device also introduces an inlet region, where wells and inlet channels synergistically contribute to the transport of approximately equal volumes of fluid from each well to every microchamber in communication with it. This design ensures a harmonized distribution of fluid, fostering consistency in exposure across the microchamber array.
Often biological samples are used to test the efficacy of a treatment option. For instance, a biological sample of a tumor tissue slice can be exposed to several treatment options and observed for cell viability and outcomes. With an effective biomimetic array device, this testing can be performed with greater precision and accuracy.
CerFlux’s biomimetic array device is not merely a technological marvel; it represents a paradigm shift in biological sample analysis. With its innovative design and meticulous attention to detail, this invention opens doors to a myriad of possibilities in therapeutic evaluation, disease modeling, and preclinical research.
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