Arizona Patent of the Month – November 2023

An allograft is tissue that is transplanted from one person to another. This is a common practice in medical applications, relying on tissue from donors. Since a donated tissue blank is typically irregular in shape, any excess portion that cannot make a full sample is wasted despite how precious the sample is.

Amnio Technology, LLC , a biotechnology company focused on optimizing the clinical use of amniotic tissue, has recently patented their allograft optimization system that aims to reduce waste.

A camera which captures a digital photograph of the irregularly shaped tissue blank is the core component. This optical system allows the system to determine the outer perimeter of the tissue blank accurately. Based on this imagery, the system determines the least wasteful cutting template for the specific tissue blank.

A cutting tray, made of magnetic metal, plays a crucial role. It provides a stable platform for the tissue blank while the cutting process takes place. The tray’s magnetic properties come into play when a plurality of perimeter retainers, each equipped with a magnet, are strategically placed along the perimeter of the tissue blank. This magnetic attraction ensures the tissue blank remains securely in place during the cutting process.

The allograft optimization computer program takes the reins, producing an optimized allograft array pattern based on the determined perimeter. This pattern includes allografts from an order log, prioritizing those with the earliest due dates. The laser cutter is then activated by an actuator to cut the allografts according to the optimized pattern.

Amnio Technology’s method stands out for its precision and adaptability. The cutting laser or tool can be moved by a robotic arm or a gantry system with two degrees of motion, ensuring accurate and controlled cutting. This flexibility is essential for handling the irregular shapes inherent in tissues like placental tissue.

The use of perimeter retainers with identifiers adds another layer of sophistication. These identifiers, recognized by the optical system, enhance accuracy in determining the tissue blank’s perimeter. Additionally, a portable cutting tray and a streamlined process for preparing the tissue blank contribute to the overall efficiency of the system.

Amnio Technology’s Allograft Optimization System represents a significant leap forward in the realm of allograft cutting. By marrying advanced optics, magnetic stability, and precise cutting technology, this system promises to revolutionize the utilization of irregularly shaped tissue blanks, ensuring that every allograft is cut with optimal efficiency and precision.

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