New York Patent of the Month – February 2023
The COVID-19 pandemic has wreaked havoc on the world, causing significant loss of life and economic devastation. With over 178 million confirmed cases and 3.8 million deaths worldwide, the need for effective treatment options is more urgent than ever before. In light of this situation, Curemark, LLC, a clinical-stage biopharmaceutical company, is working towards developing a potential treatment option for COVID-19.
Curemark is a pharmaceutical company that develops innovative treatments for a range of medical conditions. While their lead product candidate, CM-AT, is a patented enzyme-based therapy designed to address the underlying biochemistry of autism, the company directs their expertise to a number of therapies for neurological conditions and unmet medical needs. Curemark has recently patented a novel treatment pathway, leveraging the use of enzyme-based therapies to treat COVID-19 treatment, leveraging its expertise in enzyme-based therapies.
The current COVID-19 prevention and treatment guidelines are unsustainable in terms of human loss, economic impact, and the burden on the healthcare system. The long-term symptoms associated with the virus are also alarming, with the potential to damage the lungs, heart, and brain, leading to long-term health problems. There is a pressing need for a treatment option that can not only help with immediate recovery but also prevent long-term damage caused by the virus.
Curemark’s COVID-19 treatment candidate, CM-101, is a small molecule drug that has been shown to significantly reduce the production of cytokines, which are responsible for the immune system’s overreaction to the virus. This overreaction can lead to severe symptoms and damage to multiple organs, making CM-101 a promising treatment option.
The drug is currently in phase III clinical trials, and the results have been encouraging. In preclinical studies, CM-101 reduced lung inflammation and improved lung function in animal models infected with SARS-CoV-2. Additionally, the drug has been shown to reduce viral replication, leading to a faster recovery from COVID-19.
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