Ohio Patent of the Month – August 2022
While many conditions can lead to weight gain, obesity itself can result in serious complications. From diabetes to hypertension, heart failure to orthopedic problems, these complications can be life threatening. Ofcourse, it’s easy to say “just lose weight”, but this is not always a simple solution. Many people are met with binge eating disorders or hormone-induced weight regulation problems.
Gastric-bypass surgical solutions are commonly used in conjunction with stomach reduction surgeries to prevent overeating. However, these are highly invasive and may introduce additional complications. EndoSphere, Inc. has designed a non-invasive solution to curb appetite without any further issue.
Their method involves a small device to be non-invasively inserted into the small intestine. The device uses chemoreceptors to create natural hormonal responses which create signals of satiety, telling your brain that it isn’t hungry. This is achieved using bioactive materials which create a net signal of satiety. The biodegradable polymeric material of the insert allows for a controlled slow release of these bioactive materials. The physical placement of the device also activates stretch receptors which suggest your stomach is full. These active forms of intervention help curb appetite by using the body’s natural physiological responses.
The device is implanted in a way which focuses on the duodenum – the upper intestinal organ which plays an important role in the body’s Metabolic Control Center. This means there is no reliance on restricting, reducing absorption of foods, or bariatric surgeries. By placing the focus on the Metabolic Control Center instead of restricting the stomach’s available capacity or interrupting the intestinal tract’s natural absorption functions, the endo-metabolic device can effectively recreate a normal regulatory response to hunger.
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