Washington Patent of the Month – August 2025
A new patent awarded to Aurelius Biotherapeutics LLC outlines a novel cell therapy. The invention focuses on creating immune cells that specifically target and kill cancer cells. This method primes a patient’s own T cells outside the body. These cells are then administered back into the patient. This technology shows potential for treating aggressive cancers in both humans and animals, including dogs and cats.
Targeting Cancer with T Cells
U.S. Patent No. 12378522, titled ‘Cell therapy compositions and methods of use thereof’, details the innovative process. The method uses “feeder cells” to train a patient’s T cells. These feeder cells present a target protein, called CD20, found on cancer cells. This training process teaches the T cells to recognize and attack malignant cells. The approach aims to create a powerful, targeted therapy. It can be used for B cell lymphoma and other tumor types, offering a precise alternative to traditional chemotherapy.
Potential for Real-World Impact
The patent highlights the invention’s clinical relevance. Claims focus on treating B cell lymphomas in canines and felines. The technology produces a high number of specialized T cells for infusion. The patent also covers methods for preparing the patient for treatment. This includes conditioning with chemotherapy. The goal is to maximize the therapy’s effectiveness. This could lead to a new era of personalized cancer treatments, offering hope for long-term remission.
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