3D bioprinting is revolutionizing medical research. Advanced Solutions Life Sciences LLC has patented a breakthrough method for growing functional human immune tissue in a laboratory. This innovation, U.S. Patent No. 12584115, titled ‘Models and methods to establish perfusable, compartmentalized, lymphoid tissue models in three-dimensional in vitro culture’, recreates complex biological structures with precision. Scientists can now study the immune system with greater accuracy than ever before.
Replicating Human Biology
The invention uses three-dimensional culture to build functional lymphoid models. These models are perfusable, which means fluids can circulate just like they do in the human body. This constant flow is essential for keeping cells alive and healthy during long-term experiments. By compartmentalizing the tissue, the system mimics the natural organization of a human lymph node. This structural detail allows for more realistic interactions between different types of immune cells.
Better Data for Safer Drugs
This advancement offers a powerful alternative to traditional animal testing. Researchers can observe how new vaccines or therapies interact with human cells in real time. This process helps identify potential side effects before clinical trials even begin. By mimicking the human body accurately, the technology speeds up the search for life-saving treatments. It represents a significant step forward in personalized medicine and drug development.
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Are you developing new or improved products, or thinking of applying for a patent? Did you know your research work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? To find out more, please check out our free online eligibility test.
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What is the R&D Tax Credit?
The Research & Experimentation Tax Credit (or R&D Tax Credit), is a general business tax credit under Internal Revenue Code section 41 for companies that incur research and development (R&D) costs in the United States. The credits are a tax incentive for performing qualified research in the United States, resulting in a credit to a tax return. For the first three years of R&D claims, 6% of the total qualified research expenses (QRE) form the gross credit. In the 4th year of claims and beyond, a base amount is calculated, and an adjusted expense line is multiplied times 14%. Click here to learn more.
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