Illinois Patent of the Month – September 2024
Nanocytomics LLC is revolutionizing sample preparation for imaging with an innovative method designed to enhance the quality and reliability of histological and cytological analyses. This new approach addresses the inherent challenges in sample preparation, which often introduces artifacts that can compromise the accuracy of diagnostic results.
The method begins with the use of a specialized staining chamber that securely holds a staining substrate, typically a cytological slide, creating a closed staining reservoir. This configuration allows for precise control of the staining process, ensuring that liquid reagents are applied uniformly. Central to this invention is a sophisticated apparatus that includes a series of reagent vessels, enabling the introduction and removal of fluids while maintaining optimal conditions for staining.
A key innovation is the integration of a humidity control system. By managing humidity levels—whether set to around 50% or tailored to specific requirements—the method minimizes the risk of unintended artifacts caused by environmental fluctuations. This control is critical during staining, where humidity can significantly impact reagent performance and sample integrity.
The process employs automated protocols executed through an intelligent controller that regulates every aspect of staining. This includes mixing reagents using a shaker, monitoring fluid flow with sensors, and filtering excess reagents back into their respective vessels. Such automation not only enhances efficiency but also ensures repeatability across runs, a crucial factor in clinical settings.
By optimizing staining conditions and reducing waste, Nanocytomics LLC’s method promises to deliver high-quality imaging results while lowering costs. This innovation marks a significant advancement in the field of cytology, aiming to improve diagnostic accuracy and streamline workflows in laboratories worldwide.
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