Missouri Patent of the Month – July 2025
A new U.S. patent reveals an innovative approach to treating vascular obstructions. The technology uses magnetic nanoparticles and external magnetic fields. It aims to improve drug delivery and break down clots more effectively. This could provide a safer, less invasive option for patients.
Magnetism and Medicine
The new method, detailed in U.S. Patent No. 12370259, titled ‘Magnetic particle control and visualization’, was developed by Pulse Therapeutics Inc. The invention uses a magnet to create a rotating magnetic field. This field controls magnetic nanoparticles injected into a patient’s bloodstream.
Targeting Obstructions Remotely
Once injected, the nanoparticles are directed to the site of a fluid obstruction. They form tiny rods that spin rapidly. This motion creates a localized fluidic current. The current improves the mixing and diffusion of therapeutic drugs. This action increases the drug’s contact with the blockage, speeding up its breakdown. The method is designed to be gentle and non-invasive.
Reducing Drug Doses
A key benefit is the potential for lower drug doses. By enhancing the drug’s effectiveness, the technology may reduce the amount needed. This could help minimize side effects. The patent highlights its use for clearing blood clots in the brain and limbs. This offers a new tool for treating conditions like stroke and deep vein thrombosis.
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The Research & Experimentation Tax Credit (or R&D Tax Credit), is a general business tax credit under Internal Revenue Code section 41 for companies that incur research and development (R&D) costs in the United States. The credits are a tax incentive for performing qualified research in the United States, resulting in a credit to a tax return. For the first three years of R&D claims, 6% of the total qualified research expenses (QRE) form the gross credit. In the 4th year of claims and beyond, a base amount is calculated, and an adjusted expense line is multiplied times 14%. Click here to learn more.
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