Minnesota Patent of the Month – December 2025

Medical device pioneer Cryosa, Inc. is redefining sleep health with a breakthrough approach to treating obstructive sleep apnea. This innovative technology uses controlled cooling to target and reduce excess tissue in the airway. It offers a permanent, minimally invasive alternative to cumbersome CPAP masks and complex surgeries.

Cooling the airway to restore breathing

Obstructive sleep apnea (OSA) often occurs when fatty tissue at the base of the tongue or soft palate blocks airflow. U.S. Patent No. 12484950, titled ‘Systems and methods for treatment of obstructive sleep apnea’, describes a system designed to address this root cause. The device applies precise “cryolysis,” or fat-freezing, to the upper airway. This process triggers a natural reduction in tissue volume over time. By shrinking these obstructions, the system helps keep the patient’s airway open during sleep.

A patient-focused shift in OSA care

Current treatments frequently require lifelong daily compliance or invasive implants. In contrast, this new method focuses on a single, incision-free procedure performed by specialists. The system uses a specialized applicator and cooling unit to deliver thermal energy safely and effectively. This targeted cooling ensures that only the intended tissue is affected while surrounding areas remain protected. This leap in medical engineering could soon provide millions of patients with a mask-free path to a better night’s rest.

 

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