Texas Patent of the Month – February 2026
Arog Pharmaceuticals, Inc. has secured a major milestone in oncology with a newly patented treatment for aggressive cancers. This innovation focuses on U.S. Patent No. 12534764, titled ‘Crenolanib for treating FLT3 mutated proliferative disorders associated mutations’. The patent describes a targeted therapy designed to combat specific genetic mutations that often lead to drug resistance.
Overcoming Treatment Resistance
Medical researchers have long struggled with cancers that adapt to survive existing medications. Arog Pharmaceuticals, Inc. addresses this challenge through the use of Crenolanib. This compound acts as a potent inhibitor against FLT3 mutations. These mutations are common in patients with acute myeloid leukemia. By blocking these pathways, the drug prevents the rapid growth of cancer cells. This method provides a new line of defense for those who have failed other treatments.
A Leap in Personalized Medicine
This development simplifies the path toward highly personalized care. It allows doctors to tailor treatments based on the unique genetic markers of a patient. The invention demonstrates a leap forward in managing complex proliferative disorders. It emphasizes the importance of precision in modern pharmaceutical research. This advancement could significantly improve survival rates for patients facing limited options today.
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The Research & Experimentation Tax Credit (or R&D Tax Credit), is a general business tax credit under Internal Revenue Code section 41 for companies that incur research and development (R&D) costs in the United States. The credits are a tax incentive for performing qualified research in the United States, resulting in a credit to a tax return. For the first three years of R&D claims, 6% of the total qualified research expenses (QRE) form the gross credit. In the 4th year of claims and beyond, a base amount is calculated, and an adjusted expense line is multiplied times 14%. Click here to learn more.
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