New Mexico Patent of the Month – August 2025
In a move that could redefine the cannabinoid industry, a new patent reveals a biotechnological system for making these compounds water-soluble. U.S. Patent No. 12378586, titled ‘Systems, methods, and compositions for the glycosylation of cannabinoid compounds’, outlines an innovative approach. It uses a specific enzyme in a yeast cell culture. This process turns common cannabinoids like CBD and THC into water-soluble compounds. This breakthrough technology was developed by Trait Biosciences Inc.
A New Frontier for Cannabinoids
The invention addresses a major hurdle for cannabinoid products. Compounds like CBD are naturally fat-soluble. This limits their use in many common beverages and foods. It can also affect how the body absorbs them. This new system attaches a sugar molecule to the cannabinoids. This process, called glycosylation, makes them mix easily with water. This method uses a safe and scalable platform. It could lead to a new generation of products. This includes clear, consistent drinks and fast-acting edibles. The patent claims a system using yeast, such as Picha pastoris, to produce the glycosylated compounds. This promises a more efficient and predictable production method.
Real-World Impact
The innovation has significant commercial implications. Water-soluble cannabinoids offer greater flexibility for product developers. They can also improve bioavailability. This means the body can absorb the compounds more effectively. This could lead to lower doses for the same effect. It also improves product stability and consistency. The patented technology could spur a new wave of research and development. It could reshape the market for health, wellness, and consumer products.
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Are you developing new or improved products, or thinking of applying for a patent? Did you know your research work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? To find out more, please check out our free online eligibility test.
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What is the R&D Tax Credit?
The Research & Experimentation Tax Credit (or R&D Tax Credit), is a general business tax credit under Internal Revenue Code section 41 for companies that incur research and development (R&D) costs in the United States. The credits are a tax incentive for performing qualified research in the United States, resulting in a credit to a tax return. For the first three years of R&D claims, 6% of the total qualified research expenses (QRE) form the gross credit. In the 4th year of claims and beyond, a base amount is calculated, and an adjusted expense line is multiplied times 14%. Click here to learn more.
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