Patent Title: Traditional CHINESE medicine compound composition with immune bidirectional regulation effect and preparation method and applications thereof
Patent Number: 12673081
Company: Chenland Nutritionals Inc.
Inventors: Shengcan Zou, Jiancheng Zong, Haiyan Dong, Weixia Wang, Ning Ding, Lei Zong, Shanglong Wang, Chaoqi Zhao
Managing the human immune system requires a delicate equilibrium, as both underactive immune defense and overactive inflammatory responses can lead to severe health issues. Addressing this therapeutic challenge, Chenland Nutritionals Inc. has developed a novel botanical formulation grounded in traditional Chinese medicine. Their newly patented compound composition provides a bidirectional immune regulation effect, capable of boosting suppressed immune activity while simultaneously dampening hyper-inflammatory responses. By utilizing specialized extraction techniques to preserve key bioactive volatile oils and herbal extracts, this invention delivers a safe, natural, and highly effective solution for long-term immune homeostasis.
Why This Invention is Innovative
This patent introduces a unique pharmacological mechanism that overcomes the single-direction limitations of conventional immunomodulators. Traditional treatments typically focus solely on immune suppression or immune stimulation, which can lead to adverse side effects like autoimmune flares or heightened susceptibility to infections. In contrast, Chenland’s compound composition combines botanical actives like Schizonepeta (Jingjie), Astragalus, and Atractylodes using a multi-step extraction protocol. The process isolates essential volatile oils via reflux extraction before recombining them with primary herbal residues. This precise formulation dynamically modulates immune cell pathways depending on the physiological state of the host, providing target stability, high bioavailability, and negligible toxicity suitable for dietary supplements, functional foods, and pharmaceutical applications.
August 2026 Patent of the Month for the Natural-Medicine Industry
Granted in July 2026, this breakthrough formula has been rightfully awarded the Patent of the Month for the natural-medicine industry for August 2026. As the global natural medicine market increasingly demands rigorous scientific validation alongside ancient herbal wisdom, Chenland Nutritionals Inc. sets a new standard for botanical standardized extracts. By proving dual-action immunomodulatory efficacy through structured preclinical testing and repeatable batch manufacturing, this patent bridges the gap between traditional herbal practices and modern pharmaceutical requirements. Recognizing this achievement highlights the pivotal role that bio-guided extraction technology plays in modernizing natural healthcare products for commercial distribution.
Practical Applications and R&D Tax Credit Eligibility in the USA
The practical applications of this patent involve extensive botanical chemistry, extraction optimization, and pharmacological testing, making the underlying development activities highly eligible for the Research and Development Tax Credit in the United States. To qualify for this federal tax incentive, a business must satisfy a four-part test: the work must be technological in nature, serve a permitted purpose, seek to eliminate technical uncertainty, and employ a systematic process of experimentation. Formulating a compound capable of bidirectional immune regulation requires researchers to evaluate raw material ratios, design specialized solvent reflux parameters to prevent volatile compound degradation, and conduct in vitro and in vivo assays to verify dual-action physiological mechanisms. By thoroughly documenting these experimental trials, stability testing, and extraction refinement protocols, companies advancing natural drug formulations and dietary supplements can successfully claim the R&D tax credit to offset their technical development costs.
