Pathalys Pharma Secures $105M in Series B
Pathalys Pharma, a startup based in North Carolina, has raised $105 million in Series B funding. The round was led by TCGX and joined by other notable investors including, JP Morgan Life Sciences Private Capital, Samsara BioCapital, Marshall Wace, KB Investment, JPS Growth Investment Limited Partnership, and included support from Pathalys’ founding investors, Catalys Pacific and DaVita Venture Group.
Pathalys is building biotech focused on fighting kidney disease through their top candidate – upacicalcet. This candidate is a potentially improved calcimimetic for the treatment of SHPT (secondary hyperparathyroidism). A calcimimetic imitates the effects of calcium on tissues, making them excellent tools for treating problems linked to calcium homeostasis or skeletal integrity.
Upacicalcet is a novel calcimimetic which would be delivered intravenously after hemodialysis. If it operates properly, it would reduce levels of PTH and improve the tolerability profile for patients. The candidate has moved into Phase 3 Studies, with two identical 375-person trials.
The biotech stated that the additional funding will be utilized to complete those studies, start the process of getting ready to submit an application for FDA approval, and “accelerate preapproval commercialisation preparations.”
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