BeyondSpring to Host R&D Day for Plinabulin

BeyondSpring Inc. is a global leader in biopharmaceuticals with focus on cancer therapies. They have recently announced their plans to host an R&D Day to discuss the development program for their novel immune agent – Plinabulin. 

The R&D day will take place in late June with presentations from experts in the field who will highlight the unmet medical needs in treating patients with non-small cell lung cancer (NSCLC). 

They will also discuss their pipeline as it applies to their lead asset plinabulin – a selective immunomodulating microtubule-binding agent (SIMBA). Their focus will specificall be on:

  • Plinabulin and G-CSF combination, which received priority review by the U.S. Food and Drug Administration (FDA) for its NDA for prevention of chemotherapy-induced neutropenia (CIN), which also received breakthrough designation. The Company has a PDUFA date of November 30, 2021.
  • Plinabulin and docetaxel combination, which is in a fully enrolled pivotal Phase 3 global study (DUBLIN-3) as a potential direct anticancer agent in patients with NSCLC. DUBLIN-3 is expected to report data in mid-2021.
  • Plinabulin in combination immune-oncology regimens, leveraging its MOA as a potent APC (antigen presenting cell) inducer. Plinabulin has demonstrated promising Phase 1 data in 2nd/3rd line SCLC (ASCO 2021); company has recently initiated a Phase 1 study in 7 cancers which failed checkpoint inhibitors to investigate plinabulin’s potential to reverse resistance to immunotherapy.

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