MS INBRE Imaging Facility Upgrades Equipment for Research

Mississippi IDeA Network of Biomedical Research Excellence (INBRE) intends to enhance the already cutting edge technology used in their Imaging Facility.

The INBRE Imaging Core has upgraded its Leica SP8 confocal microscope to the STELLARIS STED super resolution platform to achieve one of the most complete imaging systems in the region. This imaging facility offers both imaging and microscopy expertise to researchers throughout the entire state and offers both access and training to the biomedical research equipment. 

Adding the STELLARIS STED super resolution microscope into the mix will enhance quality and scope of biomedical research throughout the state. These super-resolution microscopes open up the breadth of objects that can be imaged. Classic microscopes are limited by the physics of light itself. The super-resolution tech can image dynamic objects within cells, and even nanoparticles created in the lab. 

The Leica STELLARIS STED is an upgrade to the previous confocal microscope, offering a 3D STimulated Emission Depletion (STED) super resolution module. The STED technology enables fluorescence microscopy approaches for visualizing objects smaller than the diffraction limit of light and can increase resolution up to 10x more than a traditional microscope.

“Microscopes are essential tools for the investigation of biological and molecular systems,” Dr. Lindner, the director of the Imaging Facility, said. “Access to cutting-edge instruments is vital for cell biology, embryology, biochemistry, and imaging advanced materials. Further, the addition of the advanced microscope will provide important training opportunities for students, also enhancing Mississippi STEM education.”

Mississippi INBRE, directed by USM Professor Dr. Mohamed Elasri, is a statewide program supported by an award from the National Institutes of General Medical Sciences. Its mission is to enhance the biomedical foundation in Mississippi and engage talented researchers and students in biomedical research projects that will increase the state’s research competitiveness, as well as positively impact the health of the state’s citizens.

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