Reprieve Cardiovascular Secures $42 Million Series A Financing for Intelligent Fluid Management in Heart Failure

Reprieve Cardiovascular, Inc., a trailblazing company dedicated to innovating intelligent automated diuretic and fluid management solutions for acute decompensated heart failure (ADHF) treatment, has successfully raised $42 million in a successful series A financing round. The funding, co-led by Lightstone Ventures and Sante Ventures and joined by Deerfield Management, Genesis Capital, and Arboretum Ventures, marks a significant milestone for the company, propelling its clinical and development programs, including the ongoing FASTR trial and an upcoming pivotal trial.

Heart failure affects over 6.7 million Americans today, with ADHF causing unplanned office visits, emergency room trips, or hospitalizations due to sudden or gradual onset symptoms. Recognizing the critical need for advanced treatment options, Reprieve Cardiovascular is on a mission to transform heart failure care.

The Reprieve System aims to personalize decongestion management effectively. By monitoring physiological parameters such as urine output, the system delivers personalized diuretic dosing and fluid replacement for ADHF patients. This intelligent approach seeks to improve patient outcomes, prevent hospital readmissions, and address the challenges posed by the standard diuretic treatment option, which has remained largely unchanged for 60 years.

Mark Pacyna, CEO of Reprieve Cardiovascular, emphasized the significance of bringing intelligent decongestion management to heart failure patients. The Reprieve System offers physicians and care teams real-time visibility and control, enhancing the overall treatment process.

The company’s growth is not only reflected in its innovative solutions but also in its expanded leadership team, which includes domain experts in product development, regulatory affairs, clinical strategy, and commercialization. Mark Pacyna, with his extensive experience from Medtronic, leads this team, and the series A funding reaffirms the belief in Reprieve’s potential to revolutionize heart failure treatment globally.

Jan Garfinkle, Founding and Managing Partner of Arboretum Ventures, expressed excitement about Reprieve’s emergence from stealth mode, highlighting the pivotal trial ahead. The series A funding signifies a collective belief in Reprieve’s team and the necessity for technology that can significantly impact the lives of ADHF patients worldwide.

Reprieve Cardiovascular, headquartered in Milford, Massachusetts, is on a mission to bring intelligence to decongestion management, providing hope for more than 25 million heart failure patients globally. The ongoing FASTR trial is a testament to the company’s commitment to advancing innovative therapies and transforming heart failure care.

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