Hollywood, Florida Patent of the Year – 2024/2025
Somerset Therapeutics LLC has been awarded the 2024/2025 Patent of the Year for its innovative ophthalmic formulation. Their invention, detailed in U.S. Patent No. 11857538, titled ‘Stable pilocarpine formulations with modified buffer characteristics and related methods’, utilizes a reduced-buffer pilocarpine composition to enhance stability and patient comfort in treating presbyopia and related eye conditions.
The patented formulation features a lower buffer content and capacity compared to existing products. This adjustment maintains the solution’s stability while minimizing potential ocular irritation. By carefully balancing the concentration of pilocarpine with a uniquely characterized buffer component, the composition achieves therapeutic efficacy with improved tolerability.
Traditional pilocarpine eye drops often use higher buffer concentrations, which can lead to discomfort upon application. Somerset’s approach addresses this issue by reducing buffer strength without compromising the drug’s effectiveness. This innovation is particularly beneficial for patients requiring long-term treatment, as it may enhance adherence by reducing side effects.
The development of this formulation reflects Somerset Therapeutics’ commitment to improving ophthalmic therapies. By focusing on patient-centric solutions, the company continues to advance treatments that align with both clinical efficacy and user comfort.