Pennsylvania Patent of the Month – October 2024

Neuronasal, Inc. has developed an innovative treatment method that revolutionizes how we address brain disorders, ranging from concussions to neurodegenerative diseases. This cutting-edge approach leverages the unique properties of N-acetylcysteine (NAC), an antioxidant known for its neuroprotective benefits, and administers it intranasally. By delivering NAC directly through the nasal cavity, the treatment bypasses the blood-brain barrier—a long-standing obstacle in central nervous system therapies—allowing for targeted delivery to the brain.

This method utilizes both olfactory and trigeminal pathways to transport NAC to specific brain regions, ensuring therapeutic concentrations without systemic exposure. The result? Reduced neuro-inflammation and oxidative stress, key factors in conditions like traumatic brain injuries, dementia, and Parkinson’s disease. Unlike traditional oral or intravenous delivery systems that suffer from poor bioavailability and delayed onset, Neuronasal’s intranasal method offers rapid, localized effectiveness.

This approach minimizes the risk of systemic side effects, such as nausea and toxicity, often associated with high systemic doses of NAC. Whether administered via nasal pumps, atomizers, or nebulizers, the flexibility of this delivery method enhances accessibility and convenience for patients.

Neuronasal’s innovation holds transformative potential for sports-related injuries, age-related cognitive decline, and acute neurological conditions. With its groundbreaking focus on targeted, non-invasive treatment, this advancement represents a significant leap forward in neurotherapeutics, offering hope for improved outcomes and enhanced quality of life for countless individuals worldwide.

Are you developing new technology for an existing application? Did you know your development work could be eligible for the R&D Tax Credit and you can receive up to 14% back on your expenses? Even if your development isn’t successful your work may still qualify for R&D credits (i.e. you don’t need to have a patent to qualify). To find out more, please contact a Swanson Reed R&D Specialist today or check out our free online eligibility test.

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