Nashville, Tennessee Patent of the Year – 2024/2025
Pendant Biosciences Inc. has been awarded the 2024/2025 Patent of the Year for its innovation in controlled drug delivery. Their invention, detailed in U.S. Patent No. 11905377, titled ‘Factors controlling drug release in cross-linked poly(valerolactone) based matrices’, introduces a customizable polymer platform designed to enhance the precision and efficiency of therapeutic drug release.
Traditional drug delivery systems often struggle with inconsistent release rates and limited adaptability to different drugs. Pendant Biosciences addresses this challenge by developing a cross-linked polymer matrix that allows for tunable control over drug release profiles.
The technology utilizes a copolymer composed of poly(valerolactone), poly(allylvalerolactone), and polyethylene glycol. By adjusting the composition and cross-linking density of this matrix, the release rate of encapsulated drugs can be finely controlled. This adaptability ensures that a wide range of therapeutic agents can be delivered effectively, maintaining optimal concentrations over desired timeframes.
Such precision in drug delivery is particularly beneficial for chronic conditions requiring sustained medication levels, potentially improving patient compliance and treatment outcomes. Moreover, the biodegradable nature of the polymer matrix minimizes long-term residue in the body, enhancing safety profiles.
Pendant Biosciences’ advancement represents a significant step forward in personalized medicine, offering a versatile solution that can be tailored to meet specific therapeutic needs across various medical fields.